Primary Percutaneous Coronary Intervention and Risk of Stent Thrombosis

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Primary percutaneous coronary intervention and risk of stent thrombosis: a look beyond the HORIZON.

Primary percutaneous coronary intervention (PCI) is the preferred treatment for patients with ST-segment elevation myocardial infarction (STEMI) owing to improved vessel patency, decreased infarct size, lower rates of reinfarction, and improved survival compared with pharmacological reperfusion. However, stent thrombosis (ST) remains a major concern among STEMI patients with an excess 3to 4-fol...

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Balancing the risks of stent thrombosis and major bleeding during primary percutaneous coronary intervention.

Two feared peri-procedural complications of primary percutaneous coronary intervention (PCI) are stent thrombosis (ST) and major bleeding. Although rare, ST is associated with high rates of myocardial infarction and death. Potent antithrombotic therapy around the time of PCI markedly reduces the risk of ST, but increases bleeding hazard (Figure 1). Historically, the anticoagulant of choice for ...

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Early Stent Thrombosis and Mortality After Primary Percutaneous Coronary Intervention in ST-Segment–Elevation Myocardial Infarction

Early ST within 30 days after primary percutaneous coronary intervention (PCI) in patients with ST-segment– elevation myocardial infarction (STEMI) is a serious complication, resulting in increased mortality. Three of 4 randomized trials have demonstrated an increased risk of acute (≤24 hours) ST with bivalirudin compared with heparin with either routine or provisional glycoprotein IIb/IIIa rec...

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Comparison of long-term outcome after percutaneous coronary intervention for stent thrombosis between early, late, and very late stent thrombosis.

BACKGROUND Differences in long-term outcome between early stent thrombosis (EST), late stent thrombosis (LST), and very late stent thrombosis (VLST) are unknown. METHODS AND RESULTS A total of 152 patients who had undergone percutaneous coronary intervention for stent thrombosis between January 2001 and October 2011 were enrolled, and the clinical outcome compared between EST (55 patients), L...

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Acute stent thrombosis after primary percutaneous coronary intervention: insights from the EUROMAX trial (European Ambulance Acute Coronary Syndrome Angiography).

OBJECTIVES This study sought to determine clinical, procedural, and treatment factors associated with acute stent thrombosis (AST) in the EUROMAX (European Ambulance Acute Coronary Syndrome Angiography) trial. BACKGROUND Bivalirudin started during transport for primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction significantly reduced major bleeding ...

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ژورنال

عنوان ژورنال: Circulation

سال: 2011

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.111.023366